Patients in three groups showed no significant differences in clinicopathological characteristics including gender, age, BMI, tumor diameter, albumin, hemoglobin, platelet, total bilirubin, aspartate transaminase, alanine transaminase, pre-albumin, CRP, CA19-9, surgical methods, differentiation, 2-year survival, median survival time and chemotherapy, whereas different in lymphocyte, tumor location, and diabetes. The gene discussed is CRP; the disease is diabetes mellitus.