LNM was associated with the following clinicopathological parameters: tumor differentiation (P = 0.004), CEA (P ≤0.01), pT stage (P = 0.004), PNI (P ≤0.01), vascular infiltration (P ≤0.01), and tumor diameter (P = 0.033, Table 2). Here, CEACAM5 is linked to neoplasm.