Interestingly, it was also found that p32 depletion affected the levels of some genes reported with tumor suppressor function such as TNSF-15, HOOK-1, and PDCD4, whose expression increased, while the levels of other genes involved in promoting the malignant phenotype such as HAS-2 and MSR-1 were decreased (Table 2). This evidence concerns the gene HAS2 and neoplasm.