While JQ1 and related BET inhibitors are actively studied for inhibition of tumor cell growth, they were also shown to inhibit generation of Th17‐dependent immune reactions.7, 17 By contrast, and while JQ1 is known to inhibit DNA repair during CSR in B cells,5 its exact impact on the whole CSR process has not been documented and its global in vivo impact on immune humoral responses and on B‐cell‐dependent immune disorders, such as allergic asthma, remains to be explored. Here, DNER is linked to immune system disorder.