NFE2L2 and kidney disorder: Laboratory data indicated that ferulic acid provided beneficial properties for treatment of methotrexate‐induced renal disorder and acute kidney injury through Nrf2/ARE/HO‐1 upregulation, control of the NF‐κB inflammasome axis, a downstream molecular complex of NLRP3/caspase‐1/ASC, and modulating PPARγ expression (Mahmoud et al., 2019).