RA: rheumatoid arthritis; SLE: systemic lupus erythematosus; OA: osteoarthritis; GA: gouty arthritis; PCT: procalcitonin; CT: calcitonin; RF: rheumatoid factor; anti-CCP: anti-cyclic citrullinated peptide; anti-RA33: anti-RA33 antibodies. The gene discussed is CALCA; the disease is gout.