Moreover, the results of GO and KEGG enrichment analyses based on the GSVA algorithm also suggested high-score samples promoted tumor invasion through activating multiple pathways, including negative regulation of cell motility, cell adhesion mediated by integrin, regulation of macrophage migration, regulation of T-helper 2 cell differentiation, TGF-β signaling pathway, and so on (Figure 4(g)). The gene discussed is TGFB1; the disease is neoplasm.