To the best of our knowledge, there are no studies on these interactions in colon cancer, though several groups already highlighted the role of miR-148a regulation of ITGA5 in other cancers, namely, such observations were made and experimentally verified (luciferase reporter assays) for breast (Cimino et al., 2013), gastric (Tseng et al., 2011), and non-small cell lung (Zhang J. et al., 2019) cancers. Here, ITGA5 is linked to malignant colon neoplasm.