TNF and acute myeloid leukemia: The differentially expressed genes analyzed in the high- and low-risk groups were significantly enriched in the regulation of immune responses, including neutrophil activation, receptor ligand activity, and chemokine activity, and the main immunity-related pathways, such as acute myeloid leukemia, IL-17 signaling pathway, NF-kappa B, and TNF signaling pathways, confirmed that differentiated immune regulators were involved in these two groups.