MAPT and Alzheimer disease: The different findings regarding microbiome alterations in AD mouse models in the aforementioned studies appear to be independent of age, diet and the type of model, which was either based on Aβ pathology in the APP/PS1 (45–50, 52, 54, 55), 5XFAD (44, 53) and Tg2576 models (54), or on tau pathology in the P301L model (51).