A majority of them had a “valley” (e.g. CD4, ZAP70, Figure 8; ADA, GATA3, Supplementary Figure 8) or “descending” pattern, with expression levels decreasing from HLTY to COVID-19 and INFL (e.g. CD8, Figure 8; IL7R/IL7Rα, CD3D, IL2RASupplementary Figure 8). The gene discussed is GATA3; the disease is COVID-19.