Compared to HTLY, TUBE early and INFL had over-expression of genes involved in “human diseases”, including mainly infections (e.g. Influenza A [hsa05164], Epstein-Barr virus infection [hsa05169] or Legionellosis [hsa05134]), but also cancer (e.g. Transcriptional misregulation in cancer [hsa05202]) and inflammatory diseases (e.g. Systemic lupus erythematosus [hsa05322]). This evidence concerns the gene TUBE1 and legionellosis.