CD4 and neoplasm: While the studies mentioned above report an involvement of type 2 immunity in anti-tumor immune responses, there are also further studies existing that show a direct influence of Th2 cells on tumor growth and progression: With regard to this, A20-Ovalbumin (OVA) expressing B cell lymphomas were cleared by the injection of either OVA-specific Th1 or, importantly, Th2 CD4+ T cells into tumor bearing host mice (61).