PEAR1 and intracranial hemorrhage: PEAR1 rs12041331 A allele carrier status did not result in statistically significant differences in bleeding events (intracranial hemorrhage and any bleeding) regardless if individuals carried one (intracranial hemorrhage, P = N/A, and any bleeding, P = 0.267) or two (intracranial hemorrhage, P = 0.646, and any bleeding, P = 0.947) copies of the A allele (Table 2).