Among the AMD-associated SNPs, six of them (rs11614913, MIR196A2; rs3745198, MIR6796; rs3734050, MIR6499; rs62182086, MIR6810; and rs3746444, MIR499A; rs2925980, MIR7854) were located in miRNA genes. The gene discussed is MIR499A; the disease is age-related macular degeneration.