The functional role of certain platelet miRNAs has been recently uncovered in the platelet mRNA translation, such that miR-223 regulates the expression of P2Y12 receptor (Landry et al., 2009), VAMP8 expression is controlled by miR-96 (Kondkar et al., 2010), and miR-26b modulates SELP (P-selectin) expression in type 2 diabetes mellitus and sepsis (Fejes et al., 2017; Szilágyi et al., 2020). The gene discussed is SELP; the disease is type 2 diabetes mellitus.