Based on former results, platelet-derived miR-223 regulated EFNA1 and FBXW7 gene expression at mRNA level in HUVECs (Laffont et al., 2013), while others reported the inhibitory role of platelet miR-320b on endothelial ICAM-1 expression after myocardial infarction (Gidlöf et al., 2013). Here, ICAM1 is linked to myocardial infarction.