CASP1 mRNA levels were significantly up-regulated in AD TCX (Fig. 1h) and STG (Fig. 1i), but not in PHG (Fig. 1j), DLPFC (Fig. 1k), CER (Fig. 1l), FP (Fig. 1m), or IFG (Fig. 1n), compared to cognitively normal older adults. Here, CBLN1 is linked to Alzheimer disease.