The ZNF292 gene encodes a zinc-finger transcription factor that functions as a tumor suppressor, and eight fusion partners (B3GAT2, CGA, FIG4, GRM4, EYS, PRSS54, PTPRO, and MAP3K4) have been reported in several solid tumors (invasive breast carcinoma, lower-grade glioma, prostate adenocarcinoma, and sarcoma) in the Tumor Fusion Gene Data Portal. The gene discussed is PRSS54; the disease is invasive breast carcinoma.