The most frequent FG in AML was RUNX1-RUNX1T1 (15.2%), followed by PML-RARA (7.8%), ZNF292-PNRC1 (4.1%), NUP98-NSD1 (3.5%), CBFB-MYH11 (3.0%), KMT2A-MLLT4 (3.0%), KMT2A-MLLT3 (2.6%), KMT2A-MLLT10 (2.0%), and DEK-NUP214 (1.3%). The gene discussed is NUP214; the disease is acute myeloid leukemia.