The level of PD-L1 expression was presented as a tumor proportion score (TPS), which is the percentage of viable tumor cells showing membrane PD-L1 staining relative to all viable tumor cells and is given as 0%, 1%–49%, and ≥50%, and PD-L1 positivity was defined as ≥1% of TPS.21 22 To compensate for reader bias, all the staining results were reviewed and analyzed by two experienced pathologists who were blinded to each other’s scores and unaware of the patients’ clinical information. This evidence concerns the gene CD274 and neoplasm.