We focused our study on the classical Type II cadherins cadherin-8 (Cdh8, CDH8) and cadherin-11 (Cdh11, CDH11) as these specific cadherins have been identified as autism risk genes in a genome-wide association study and by whole exome sequencing (Hussman et al., 2011; Cukier et al., 2014). The gene discussed is CDH8; the disease is autism.