Although none of these individuals carried risk variants in either of these cadherins (DeRosa et al., 2018), CDH8 levels were significantly increased (control: 0.0614 ± 0.0108, autism: 0.1186 ± 0.0086; Fig. 5A), whereas CDH11 levels were significantly decreased (control: 0.4200 ± 0.1520, autism: 0.0821 ± 0.0621; Fig. 5B) in iPSC-derived cortical NPCs from autistic individuals compared with neurotypical control cells. This evidence concerns the gene CDH17 and autism.