According to bioinformatics results, among important molecular pathways enriched by the webgestalt database, PI3K-Akt signaling pathway and regulation of PTEN mRNA translation are important enriched signaling pathways in which the targets of miR-152-3p are involved, and there may be a relationship between miR-152-3p expression and BC chemoresistance. This evidence concerns the gene AKT1 and breast cancer.