We found a moderate but highly significant negative correlation between high SMAD1 expression and KEGG Apoptosis pathway inhibition across the ~ 1000 CCLE cell lines (R = -0.1486, p < 0.0001) (Fig. S2A); an enrichment of apoptosis inhibition (high Z score) was also observed in other hematological malignancies (Fig. S2 B-F). The gene discussed is SMAD1; the disease is hematologic disorder.