At the EoT, no significant changes were observed in hematological parameters except for a slight increase of MHC in AgAc-treated mice that is likely not biologically relevant, since MCHC (the other indicator of intraerythrocytic haemoglobin) did not significantly increase and changes of MCH and MCHC are considered pathophysiologically relevant when anemia is present, which was not the case [56, 57]. This evidence concerns the gene HLA-C and anemia.