MKI67 and neoplasm: Increased TACC3 levels were significantly associated with tumor differentiation (P = 0.004), histological type (P = 0.006), parametrium invasion (P = 0.040), nerve invasion (P = 0.003), surgical margin (P = 0.012), P16 (P < 0.001), and Ki-67 (P = 0.004) (Table 1).