In addition to NECTIN2 and PLPP3, 15 other annotated immune or inflammation associated genes had significantly lower gene expression in T2D neutrophils (Table 2), while KCNH4, GNPDA1, TLCD2, VEGFA, MFSD2A, PNPLA1, GPR4, and LPCAT1 showed lower expression in T2D neutrophils and had previously been linked to lipid or glucose metabolism. The gene discussed is GPR4; the disease is type 2 diabetes mellitus.