HTRA3 and type 2 diabetes mellitus: However, the genes differentially expressed between T2D and healthy neutrophils in the cell culture perturbation model without RvE1 treatment were generally not the same as the significant differentially expressed serum neutrophil genes observed in the main analysis, with the exception of NECTIN2, HTRA3, and ABCG1, which were differentially expressed in both serum and cell culture.