TF and hepatocellular carcinoma: To investigate the end‐motif patterns in our data, we first counted the proportions of six representative end motifs (CCCA, CCTG, CCAG, TAAA, AAAA and TTTT), reported previously [15], in high‐TF (TF > 0.2) HCC, low‐TF (0 < TF ≤ 0.2) HCC, and HBV groups.