Li Li P P Zhang Zhang L L Zhang Zhang M M Zhou Zhou C C Lin Lin N N Uric acid enhances pkc-dependent enos phosphorylation and mediates cellular er stress: A mechanism for uric acid-induced endothelial dysfunction Uric acid enhances pkc-dependent enos phosphorylation and mediates cellular er stress: A mechanism for uric acid-induced endothelial dysfunction Int J Mol Med Int J Mol Med 2016 2016 37 37 4 4 989 989 997 997 26935704 26935704. This evidence concerns the gene NOS3 and endothelial dysfunction.