As for hsa_circ_0004913, it recovers the expression of INPPL1 repressed by miR-184 [9] and previous study proved that over expressing INPPL1 or miR-184 silencing inhibits HCC proliferation [32], which indicates that hsa_circ_0004913 may exert an anticarcinogenic effect on HCC. Here, INPPL1 is linked to hepatocellular carcinoma.