Nevertheless, positive CSF CXCL13 results in both assays were also found in a definite-LNB patient who had a normal blood-CSF barrier in the absence of intrathecal total-antibody synthesis (Reibergram area 1 [i.e., group 1]) and in two patients (one diagnosed with definite LNB and the other with tuberculous meningitis) who had a dysfunctional blood-CSF barrier and no proof of intrathecal total-antibody synthesis (Reibergram area 2 [i.e., group 2]). The gene discussed is CXCL13; the disease is meningeal tuberculosis.