F2 and hyperinsulinemic hypoglycemia, familial, 4: Inherited PTS is comprised by a factor V Leiden acquired mutation (FVL), deficiency of antithrombin (AT) III, protein C (PC) or S (PS), histidine‐rich glycoprotein deficiency, prothrombin‐related thrombophilia, prothrombin 20210A mutation, elevated factor VIII level, and mutations of the gene encoding the enzyme methylenetetrahydrofolate reductase.