It is a multifunctional RNA-binding protein that is overexpressed in glioma, a type of tumor that occurs in the brain, and a decreased expression of PTBP inhibits cell migration and increases the adhesion of cells to fibronectin and vitronectin (Cheung et al., 2009; Shibayama et al., 2009). The gene discussed is FN1; the disease is glioma.