MTHFD1L and cancer: With respect to the shared differentially expressed proteins, several of these proteins have previously been implicated in cancer biology, such as decreased MAOB (Ryu et al., 2018) and HK1 (Rai et al., 2019), and increased MTHFD1L (Lee et al., 2017), and COX17 (Singh et al., 2020; Figure 4A).