In breast cancer cells, silencing of the Rab11 regulator Rabgap1 impairs active β1 integrin recycling and migration31, whereas Rab11b upregulation during early adaptation to the brain metastatic sites favors successful β1 integrin recycling to the surface and interaction with the ECM, promoting mechanotransduction-activated survival32. Here, RAB11A is linked to breast carcinoma.