In TNBC, synaptotagmin-like 4 (SYTL4) contributes to taxane resistance via attenuating the stability of microtubule network and increasing the growth rate of microtubule 53 The antisense intronic lncRNA (ai-lncRNA) EGOT (eosinophil granule ontogeny transcript) sensitizes breast cancer cells to paclitaxel by enhancing autophagy54. Here, SYTL4 is linked to breast cancer.