TRPV1 and lung cancer: In 2016, Nishino et al. reported that pretreatment with the TRPV1 channel inhibitors capsazepine, SB366791, AMG9810, and BCTC suppressed repair of γ-ray-induced-DNA-damage in human lung cancer A549 cells, indicating TRPV1 antagonists may serve as radiosensitizers, enhancing the efficacy of radiation therapy 118.