FTO and obesity due to melanocortin 4 receptor deficiency: FTO variants (rs11642841, rs1421085, rs17817449, rs3751812, rs9939609), which have been linked to obesity in six Arab countries (Table 1, Fig. 3), and according to the clinical phenotype, they are considered as “common variants”; as they were found to be associated with obesity in other non-Arab countries, including China, Croatia, and Brazil (Table S3).