ITGAM and cancer: In this regard, neutrophils are able to kill antibody opsonized cancer cells through a new way of cell death named as trogoptosis41, which involves CD11b/CD18-dependent neutrophil-tumor cell conjugate formation, followed by an antibody-mediated trogocytosis through neutrophils exerting an active mechanical disruption of the cancer cell plasma membrane, leading to a lytic (i.e., necrotic) type of cancer cell death.