ALOX12 and cancer: Indeed, the levels of the oxidized phosphatidylethanolamine (PE) and phosphatidylcholine (PC) (oxPE (18:0/22:4)sn2 or oxPC (18:0/20:4)sn2) were significantly induced upon ALOX12 expression, indicating that ALOX12 is critical for generating oxidized PE and oxidized PC in human cancer cells (Fig. 7g, h and Supplementary Fig. 9a–c).