ITGAM and neoplasm: Compared with tumors in WT mice, tumor-immune infiltrates in Ppm1dFes-cre mice exhibited significantly increased proportions of CD11b + myeloid cells, unchanged proportions of F4/80+ tumor-associated macrophages (TAMs), and significantly increased proportions of Ly6G+ tumor-associated neutrophils (TANs) (Fig. 2d).