In combination, the observed substantial increase in tumor infiltration by Wip1-deficient neutrophils, but not Wip1-deficient macrophages (Fig. 2d), and the complete reversal of tumor suppression in Wip1-deficient mice by depletion of neutrophils (Fig. 2f), suggests that Wip1-deficient neutrophils are primarily responsible for the observed phenotype in our models. Here, PPM1D is linked to neoplasm.