For example, miR-103 promotes proliferation and metastasis by targeting KLF4 in gastric cancer [32] and regulates triple-negative breast cancer cell migration and invasion by targeting olfactomdin4 [33], while miR-103a functions as a tumour suppressor by directly targeting programmed cell death 10 in NSCLC [34]. This evidence concerns the gene KLF4 and non-small cell lung carcinoma.