By leveraging guilt by association, we prioritize BDH1, CEP19, DLG1, FBXO45, PIGZ, RNF168, SENP5, UBXN7, and WDR53, along with their 284 unique SZ, ASD, and/or IDD-related top neighbors from significant overlap tests as likely drivers of the neuropsychiatric consequences of 3q29Del (Fig. 4a and Table S2.3). This evidence concerns the gene SENP5 and intervertebral disk degenerative disorder.