These include MECP2, NRXN1, GRIN2A, GRIN2B, CHD8, SATB2, CNTNAP2, FOXP1, PTEN, and SCN2A. Motivated by this observation, we asked whether top neighbors of individual 3q29 genes significantly overlap with known SZ, ASD, or IDD-risk genes (Fig. 3a). This evidence concerns the gene NRXN1 and intervertebral disk degenerative disorder.