These include MECP2, NRXN1, GRIN2A, GRIN2B, CHD8, SATB2, CNTNAP2, FOXP1, PTEN, and SCN2A. Motivated by this observation, we asked whether top neighbors of individual 3q29 genes significantly overlap with known SZ, ASD, or IDD-risk genes (Fig. 3a). The gene discussed is MECP2; the disease is intervertebral disk degenerative disorder.