FBXO45 and intervertebral disk degenerative disorder: By leveraging guilt by association, we prioritize BDH1, CEP19, DLG1, FBXO45, PIGZ, RNF168, SENP5, UBXN7, and WDR53, along with their 284 unique SZ, ASD, and/or IDD-related top neighbors from significant overlap tests as likely drivers of the neuropsychiatric consequences of 3q29Del (Fig. 4a and Table S2.3).