SLC4A11 and Fuchs endothelial corneal dystrophy: Moreover, SLC4A11, localized at the basolateral surface of CECs, contributes to osmotically-driven water flux from the stroma to aqueous humor to maintain the relative dehydration of the cornea [80], and four mutations associated with corneal endothelial dystrophy can impair solute transport (water flux) function [80, 81].