ITGA11 and diabetic cardiomyopathy: Itga11 (Integrin Subunit Alpha-11) expression has been detected to be increased in methylglyoxal-induced collagen-treated human cardiac fibroblasts and streptozotocin-treated Sprague–Dawley rat cardiac fibroblasts, which may promote the formation of pre-fibrotic fibroblasts and fibrotic stroma in diabetic cardiomyopathy [36].