EPG5 and cerebellar ataxia: Such a period of accelerated deterioration, characterized by progressive dementia, epilepsy and movement disorders (often of a Parkinsonian nature) is typical in WDR45-associated BPAN and SNX14-associated cerebellar ataxia, but also in EPG5-related Vici syndrome, as evidenced by rapidly progressive microcephaly and an evolving movement disorder in long-term survivors.