However, published studies have reported the low risk of SARS-CoV-2 transmission in educational settings as well as differences in infection rates within households by age group.17, –19 The prevalence of gastrointestinal symptoms including diarrhea, vomiting, and poor feeding, which have been associated with MIS-C, were also associated with severe/critical infection.20 Raised C-reactive protein values in COVID-19 cases were only evident in Pakistan, which is not surprising because all cases were admitted to the ICU. The gene discussed is CRP; the disease is COVID-19.