PTH and hypertensive disorder: Furthermore, PTH and angiotensin II receptors have been found on osteoblast cell lines that directly regulate bone turnover.[9,10] Secondary PTH increase can also directly lead to increased bone resorption and high bone turnover, which may lead to bone loss.[20] In our study, after the potential confounders were adjusted, 25-OHD level was found to be significantly lower in hypertensive male group than that in male without hypertension group.