ESAM and neoplasm: First, the inflammatory factors AST, ALT, ALP, MIP-1α, MIP-3α, and MCP-1 were positively correlated with the transcription of genes related to cytokine secretion (Lilrb4 and Ackr3) and cell carcinoma growth (Rock2, Socs5, Serpine1, Plau, Plod2, and Col12a1) and with proteins related to tumor-associated biomarkers (EMD, NAP1L1, STMN1, EZR, and STMN2), immune suppressors (KIF13B, TUBB5, UBE2D3, GBP7, ESAM, and CASP1), inducers of hepatic injury (KDSR and DEFA5), and lipid metabolic proteins (PON3, DDB1, RDH10, and LPL).