FSTL3, an indicator of Activin/TGFβ signaling, was the most significantly upregulated protein associated with the heart failure biomarker, NTproBNP (β = 0.4;p <sub>adj</sub> =4.6x10 <sup>- 7</sup> ), while ADAMTS13, a vWF-cleaving protease whose loss-of-function causes microvascular thrombosis, was the most downregulated protein associated with myocardial injury (β=-0.4;p <sub>adj</sub> =8x10 <sup>- 7</sup> ). This evidence concerns the gene ADAMTS13 and heart failure.