FOXM1 and cholangiocarcinoma: To investigate whether FoxM1 could regulate the effects of avasimibe on cholangiocarcinoma cells proliferation, we overexpressed FoxM1 in RBE cells and QBC9393 cells before avasimibe treatment, and we found FoxM1 overexpression could counteract the effects of avasimibe on cholangiocarcinoma cells proliferation (Figures 6A, B).