PDK1 and posterior cortical atrophy: Similar results were also obtained when we replaced miR-125-2-3p with miR-4736 binding to the wild-type PDK1 3′UTR via insertion of the 972-bp fragment from the PDK1 3′UTR with the predicted miR-4736 target site into the psiCHECKTM-2 vector as well as a mutated version at the predicted target site in the same PCa and BCa cells (Fig. 4J).