After adjustment of age, gender, body mass index, etiology, hypertension, diabetes mellitus, white blood cell, C-reactive protein, procalcitonin, alanine aminotransferase, total bilirubin, blood urea nitrogen, serum creatinine, PaO2/FiO2, systolic blood pressure, intra-abdominal hypertension, modified Marshall score, BISAP score, total fluid, time of blood volume expansion, binary logistic regression analysis revealed that there was no significant correlation between the types of fluid resuscitation and 90-day mortality (Table 8). This evidence concerns the gene CRP and hypertensive disorder.